Evidence of PEMF using Darkfield microscopy
There are still only a few reproducable measuring applications to proof the immediate effects of PEMF’s on human organisms. Within the field of complementary and alternative medicine, dark field microscopy is one of the most common and used methods. By taking a blood sample and putting it under a special microscope, red blood cells can be observed before and after an PEMF application with a whole body applicator. Watch the video below to observe the difference in membrane potential before and after a PEMF application.
(The following research is a service of the U.S. National Library of Medicine and the National Institutes of Health for the National Center for Biotechnology Information (NCBI) @ http://www.pubmed.gov Established in 1988 as a national resource for molecular biology information, NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information – all for the better understanding of molecular processes affecting human health and disease. )
To see the complete research abstract from the following examples go to http://www.pubmed.gov and put the PMID number in the search box.
Alzheimer’s disease
Impairments in visual memory and visuoconstructive functions commonly occur in patients with Alzheimer’s disease (AD). Recently, I reported that external application of electromagnetic fields (EMF) of extremely low intensity (in the picotesla range) and of low frequency (in the range of 5Hz-8Hz) improved visual memory and visuoperceptive functions in patients with Parkinson’s disease. The report demonstrates, for the first time, that specific cognitive symptoms of AD are improved by treatment with EMF of a specific intensity and frequency. The rapid improvement in cognitive functions in response to EMF suggests that some of the mental deficits of AD are reversible being caused by a functional (i.e., synaptic transmission) rather than a structural (i.e., neuritic plaques) disruption of neuronal communication in the central nervous system. – International Journal of Neuroscience PMID: 7960477
Repetitive transcranial magnetic stimulation applied to the dlPFC improves naming performance also in the advanced stages of AD. Moreover, in the severe group the effect is not specific for action naming, as in the case of the mild AD group. These findings suggest that rTMS can affect the intrinsic ability of the brain to restore or compensate for damaged function and may represent an useful new tool for cognitive rehabilitation. – European Journal of Neurology PMID: 19049544
Ankle sprain
Acutely sprained ankles represent a frequent and common injury among active duty troops in training, and are a significant source of morbidity with respect to days lost to training. In a randomized, prospective, double blind study of 50 grade I and II (no gross instability) sprained ankles, a statistically significant decrease in edema was noted following one treatment with pulsed electro magnetic field (PEMF) therapy. The application of this modality in acutely sprained ankles could result in significant decreases in time lost to military training. – Military Medicine PMID: 8441490
Back pain
Back pain and the whiplash syndrome are very common conditions involving tremendous costs and extensive medical effort. A quick and effective reduction of symptoms, especially pain, is required. Magnetic fields appear to have a considerable and statistically significant potential for reducing pain in cases of lumbar radiculopathy and the whiplash syndrome. – Neuro Rehabilitation PMID: 12016348
Back pain – low back
This randomized, double-blind, placebo-controlled clinical trial studied the effectiveness of pulsed electromagnetic therapy (PEMT) in patients with chronic lower back pain. PEMT produced significant pain reduction throughout the observation period compared with baseline values. The percentage change in the NRS score from baseline was significantly greater in the PEMT group than the placebo group at all three time-points measured. The mean revised Oswestry disability percentage after 4 weeks was significantly improved from the baseline value in the PEMT group, whereas there were no significant differences in the placebo group. In conclusion, PEMT reduced pain and disability and appears to be a potentially useful therapeutic tool for the conservative management of chronic lower back pain. – Journal of International Research PMID: 16749411
We evaluate the efficacy and safety of therapeutic electromagnetic fields (TEMF) on chronic low back pain. Secondary objectives included the investigation of the effects of TEMF on psychometric measures. Both groups improved over time. Although groups were similar during the treatment period, treated subjects (TEMF of 15 mT) improved significantly over sham treatment during the 2-week follow-up period (20.5% reduction in pain); There were no reported serious adverse events. This study demonstrates that TEMF may be an effective and safe modality for the treatment of chronic low back pain disorders. – Pain Practice PMID: 17714104
Bone density
To determine the effect of a 72 Hz pulsating electromagnetic field (PEMF) on bone density of the radii of osteoporosis-prone women, the nondominant forearms of 20 subjects were exposed to PEMF 10 h daily for a period of 12 weeks. The data suggest that properly applied PEMFs, if scaled for whole-body use, may have clinical application in the prevention and treatment of osteoporosis. – The Journal of Bone and Mineral Research PMID: 2195843
Cancer – bladder
The study deals with immune status of patients operated for bladder cancer and exposed postoperatively to alternating magnetic field (MF). MF application was followed by higher T- and B-lymphocyte and CD4+, CD16+ cell levels as well as enhanced T-cell activity; no postoperative complications were registered and tumor relapse rates were relatively low. The effect was likely to be due to antistressor influence of MF. The procedure may substitute drug therapy for immunocorrection and to avoid recurrence of bladder cancer. – Volpr Onkol PMID: 11544830
Cancer – breast tumors
The study was concerned with effect of alternating magnetic field (AMF) on immunobiological characteristics of lymphocytes from patients with locally-advanced breast tumors. Patients received infusions of treated autoblood and changes in their immunological status were followed up. Stimulation of T-, B- and NK- cells was observed. Immuno-regulating effect was apparent when autoblood was treated with 50 H/25 mT1 and 100 H/50 mT1. – Volpr Onkol PMID: 15088521
Cancer – cells
PEMF promotes the growth of undifferentiated cells but progressively suppresses the growth of more differentiated cells, i.e., PEMF controls cell growth depending on the degree of cell differentiation. This study also shows the potentiality of PEMF as an adjunctive treatment method for malignant tumors. – Bioelectromagnetics PMID: 10653622
No adverse side-effects were reported in an investigation of the antitumor effect of turbulent magnetic field (TMF) carried out as a component of preoperative chemoradiotherapy for breast cancer at the Center’s Clinic. The study group included 114 patients with locally advanced tumors(T3, N1-N3, M0). According to the clinical, roentgenological and histological evidence on the end-results, the procedure was highly effective. Also, it was followed by shorter and less extensive postoperative lymphorrhea. – Volpr Onko PMID: 14976921
Carpal Tunnel Syndrome PEMF exposure in refractory carpal tunnel syndrome provides statistically significant short and long-term pain reduction and mild improvement in objective neuronal functions. Neuromodulation appears to influence nociceptive-C and large A-fiber functions, probably through ion/ligand binding. – Pain Medicine PMID: 18777606
Cartilage
Severe joint inflammation following trauma, arthroscopic surgery or infection can damage articular cartilage, thus every effort should be made to protect cartilage from the catabolic effects of pro-inflammatory cytokines and stimulate cartilage anabolic activities. Previous pre-clinical studies have shown that pulsed electromagnetic fields (PEMFs) can protect articular cartilage from the catabolic effects of pro-inflammatory cytokines, and prevent its degeneration. The percentage of patients who used NSAIDs was 26% in the active group and 75% in the control group. At 3 years follow-up, the number of patients who completely recovered was higher in the active group compared to the control group. Treatment with I-ONE aided patient recovery after arthroscopic surgery, reduced the use of NSAIDs, and also had a positive long-term effect. – Knee Surgery, Sports Traumatology, Arthroscopy PMID: 17333120
Chronic pain
Specific pulsed electromagnetic fields (PEMFs) have been shown to induce analgesia (antinociception) in healthy human volunteers. These findings provide some initial support for the use of PEMF exposure in reducing pain in chronic pain populations and warrants continued investigation into the use of PEMF exposure for short-term pain relief. – Pain Research & Management PMID: 16770449
Dental pain
Two hours of exposure to a weak, oscillating magnetic fields induced a significant decrease in three parameters (dental sensory and cutaneous pain and tolerance thresholds), whereas the other two parameters showed a similar tendency. When the same subjects were exposed to a sham treatment, only marginal, nonsignificant variations in all parameters were observed. These results represent the first piece of evidence that weak alterations of the magnetic field may induce hyperalgesia in humans. – Bioelectromagnetics PMID: 8554630
Diabetic neuropathy/angipathy
Significant improvement of symptoms, and of all registered parameters of peripheral circulation was established after the therapy. High-frequency pulsating electromagnetic field is recommended for the treatment of diabetic angiopathy. In patients with neuropathic changes it can be used as an introduction procedure. – Srpski arhiv za celokupno lekarstvo PMID: 7725151
This study demonstrates that pulsed electromagnetic fields are able to accelerate wound healing under diabetic and normal conditions by up-regulation of FGF-2-mediated angiogenesis. They also prevented tissue necrosis in response to a standardized ischemic insult, suggesting that noninvasive angiogenic stimulation by pulsed electromagnetic fields may be useful to prevent ulcer formation, necrosis, and amputation in diabetic patients. – Plastic and Reconstructive Surgery PMID: 18176216
Erectile dysfunction
Combined treatment with local negative pressure and pulsating magnetic field conducted in 116 patients with erectile dysfunction aged 20-60 years produced optimal treatment results. Recovery and improvement of the erectile function were achieved in 85.7% patients given local vacuum magneto-therapy. – Vopr Kurortol Fizioter Lech Fiz Kult PMID: 17882824
An effect was studied of appliances for magneto-therapy on sexual function of 105 men presenting with sexual problems. A total of 96 sexological patients were examined according to a general program, to study placebo-effect. The magnetic field beneficial effect was recordable in 70-80 % of the patients, that of placebo in 33 % men. It is suggested that augmentation of sexual activity is associated with an increase in cavernous blood flow. – Lik Sprava PMID: 8819933
Fibromyalgia
Exposure to a specific pulsed electromagnetic field (PEMF) has been shown to produce analgesic (antinociceptive) effects in many organisms. In a randomized, double-blind, sham-controlled clinical trial, patients with either chronic generalized pain from fibromyalgia (FM) or chronic localized musculoskeletal or inflammatory pain were exposed to a PEMF (400 microT) through a portable device fitted to their head during twice-daily 40 min treatments over seven days. PEMF may be a novel, safe and effective therapeutic tool for use in at least certain subsets of patients with chronic, nonmalignant pain. – Pain Research & Management PMID: 18080043
Heart rate variability
Exposure to PEMF for 20 minutes resulted in more rapid recovery of heart rate variability, especially in the very low frequency range after physical strain. The study also showed the moderating influence of the subjects’ constitutional VLF power on their response to PEMF treatment. These findings have since been replicated in a clinical study and should be taken into consideration when PEMF treatment is chosen. – European Journal of Applied Physiology PMID: 17674028
Inflammation
It is well known that electromagnetic fields (EMFs) can induce repair of non-healing bone fractures. It is generally believed that non-invasive, EMF therapy might have a broad, albeit currently unrecognized clinical potential. Since T cells are key modulators of inflammation, the development of EMF based therapeutic devices to regulate their activity can be expected to provide important tools to treat numerous human inflammatory diseases such as psoriasis and arthritis. – Biomedical Sciences Instrumentation PMID: 10834201
Knee pain
Low-amplitude, extremely low frequency magnetic fields are safe and effective for treating patients with chronic knee pain due to osteoarthritis. Reduction in pain after a treatment session was significantly greater in the magnetic field-on group (46%) compared to the magnetic field-off group (8%). – Alternative Therapies in Health and Medicine PMID: 11565402
Knee arthritis
In patients with symptomatic osteoarthritis of the knee, PMF treatment can reduce impairment in activities of daily life and improve knee function. – Wiener Klinische Wochenschrift PMID: 12602111
Lumbar fusion
Sixty-one randomly selected patients who underwent lumbar fusion surgeries for discogenic low back pain between 1987 and 1994 were retrospectively studied. All patients had failed to respond to preoperative conservative treatments. Forty-two patients received adjunctive therapy with pulsed electromagnetic field (PEMF) stimulation, and 19 patients received no electrical stimulation of any kind. Average follow-up time was 15.6 months postoperatively. Fusion succeeded in 97.6% of the PEMF group and in 52.6% of the unstimulated group. The use of PEMF stimulation enhances bony bridging in lumbar spinal fusions. Successful fusion underlies a good clinical outcome in patients with discogenic low back pain. – Advances in Therapy PMID: 11010056
Migraine/Headaches
In the active-treatment group, all assessed criteria were significantly improved at the end of the migraine/headache study. 76% of active-treatment patients experienced clear or very clear relief of their complaints. Only 1 placebo-patient (2.5%) felt some relief; 8% noted slight and 2% reported significant worsening of symptoms. No side effects were noted. – Advances in Therapy PMID: 11571822
Ten of the 22 subjects who had actual exposure received 2 additional weeks of actual exposure after their initial 1-month follow-up. All showed decreased headache activity (50% good, 38% excellent). Thirteen subjects from the actual exposure group elected not to receive additional exposure. Twelve of them showed decreased headache activity by the second month (29% good, 43% excellent). Eight of the subjects in the placebo group elected to receive 2 weeks of actual exposure after the initial 1-month follow-up with 75% showing decreased headache activity (38% good, 38% excellent). In conclusion, exposure to pulsing electromagnetic fields for at least 3 weeks is an effective, short-term intervention for migraine, but not tension headaches. – Headache PMID: 11279973
Multiple Sclerosis
There is a growing literature on the biological and clinical effects of pulsed electromagnetic fields. Some studies suggest that electromagnetic therapies may be useful in the treatment of chronic illnesses. This study is a follow-up to a placebo controlled pilot study in which multiple sclerosis (MS) patients exposed to weak, extremely low frequency pulsed electromagnetic fields showed significant improvements on a composite symptom measure. Evidence from this randomized, double-bind, placebo controlled trial is consistent with results from smaller studies suggesting that exposure to pulsing, weak electromagnetic fields can alleviate symptoms of MS. – Alternative Therapies in Health and Medicine PMID: 12868251
Fatigue is the most common symptom of multiple sclerosis. 75%-90% of patients with multiple sclerosis report having fatigue, and 50%-60% describe it as the worst symptom of their disease. Fatigue is significantly associated with reduced quality of life and is also a major reason for unemployment, especially for patients with otherwise minor disability. There is evidence that pulsing electromagnetic fields may improve fatigue associated with multiple sclerosis. – Wien Med Wochenschr. PMID: 12658965
Recent clinical reports have suggested that treatment with extremely weak magnetic fields (MF) in the picoTesla range is an efficacious modality for the symptomatic therapy in patients with multiple sclerosis (MS) during the remission and exacerbation periods of the disease. The report attests to the unique efficacy of extremely weak MF in the symptomatic treatment of patients with MS including those patients with a chronic progressive course of the disease and supports the hypothesis that dysfunction of synaptic conductivity due to neurotransmitter deficiency specifically of serotonin rather than demyelination underlies the neurologic deficits of the disease. – International Journal of Neuroscience PMID: 8063544
We performed a double-blind study to measure the clinical and subclinical effects of an alternative medicine magnetic device on disease activity in multiple sclerosis (MS). there was a significant improvement in the performance scale (PS) combined rating for bladder control, cognitive function, fatigue level, mobility, spasticity, and vision (active group -3.83 +/- 1.08, p < 0.005; placebo group -0.17 +/- 1.07, change in PS scale). There was also a significant change between pretreatment and posttreatment in alpha EEG magnitude during the language task recorded at various electrode sites on the left side. – Journal of Alternative and Complementary Medicine PMID: 9395691 Myofascial pain The repetitive magnetic stimulation (rMS) group showed a significant improvement in VAS, NPDVAS, algometry, as well as in the characteristics of the therapy device after conclusion of treatment. Improvements in the ROM were also present in rotation and controlateral bending. This improvement persisted after 1 month. On the other hand, the placebo group did not show any significant improvement in the tests considered. The results of this study show that peripheral repetitive magnetic stimulation (rMS) may have positive short- and medium-term therapeutic effects on myofascial pain. – Clinical Neurophysiology PMID: 12559244 Neck pain Patients' with chronic neck pain preferences were for pulsed electro magnetic field (PEMF). At 6 months, in the PEMF group, 33 patients were improved, 5 not improved and 4 lost to follow-up. In the spa therapy group, 24 patients were improved, 14 not improved and 6 lost to follow-up, for significantly greater improvement in the PEMF than spa therapy group (p=0.02). Significant improvement was seen in both groups in terms of pain score, Copenhagen scale score and score on some dimensions of the MOS SF-36 survey. PEMF seems to be superior to standard spa therapy group without massage in control of neck pain. The difference between groups, although perhaps biased, seems to suggest the importance of our conclusions. – Annales de Readaptation et de Medecine Physique PMID: 17229483 Neuralgia Pulsed radiofrequency treatment has been described as a minimal invasive alternative to radio-frequency thermocoagulation for the management of chronic pain syndromes. We present here our first five high-risk patients with idiopathic trigeminal neuralgia who were treated with pulsed radiofrequency after multidisciplinary assessment; with a mean follow-up of 19.2 months (range 10-26). These patients were at high risk due to age, co-morbidities or previous interventional and surgical treatments. An excellent long-term effect was achieved in three of the five patients, a partial effect in one patient and a short-term effect in one patient. No neurological side effects or complications were reported. – International Association for the Study of Pain PMID: 12927617 Neuropathy Ilioinguinal neuropathy is a rare but disabling condition. The condition may arise spontaneously or in the setting of pelvic surgery. To date, most therapeutic options have been limited to neuropathic pain medications, anti-inflammatory medications, nerve blocks with local anesthetics, or neurectomy. Long-term results of non-surgical interventions are fair at best. Pulsed radiofrequency lesioning may be a good treatment for chronic ilioinguinal neuropathy in cases refractory to conservative management. – Journal of Hernias and Abdominal Wall Surgery PMID: 17273814 The largely unsatisfactory results reported for the pharmacological treatment of diabetic neuropathy has spurred the search for alternative therapies. Frequency-modulated electromagnetic neural stimulation (FREMS) induced a significant reduction in daytime and night-time VAS pain score (all p<0.02). furthermore, frems induced a significant increase in sensory tactile perception, as assessed by monofilament; decrease foot vibration perception threshold, measured biothesiometer; and an motor nerve conduction velocity (all p<0.01). no changes were observed after placebo. comparison of measurements at the 4-month follow-up with those baseline revealed that benefit persisted for all measures showed improvement end treatment, additional quality life (short form-36 questionnaire)no side effects recorded during study. frequency-modulated electromagnetic neural stimulation (frems) is safe effective therapy neuropathic pain patients diabetes able to modify some parameters peripheral function. – diabetologia pmid: 15834546 clinical electroneuromyographic studies performed 121 diabetic polyneuropathy (dpn) before courses treatment pulsed fields 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appears influence nociceptive-c large a-fiber functions, probably through ion/ligand binding. medicine 18777606 parkinson’s disease since brief, extracerebral applications pico-tesla (pt) range flux intensity (emfs) been shown produce rapid cognitive pd, expected emfs would lead also visual evoked (vep) response. study demonstrates parkinsonian rapidly vep response and, inference, cerebral dopamine levels presumably increasing release. international 8707479 pelvic unusually long-lasting relief gynecological origin obtained consistently short exposures affected areas magnetic induction device producing short, sharp, magnetic-field pulses minimal initiate electrochemical phenomenon electroporation within 25 cm2 focal area. treatments fasting-acting, economical many instances obviated surgery. european surgery 7531030 rotator cuff tendonitis value persistent tested double-blind controlled 29 whose steroid injection other conventional conservative measures. 19 (65%) symptom-less 5 others much improved. may thus useful possibly tendon lesions. lancet 6143039 sacral roots used neurologic examination. however, reported efficacy pudendal neuralgia stimulation. immediately eliminated lasted between 30 minutes 56 days (median, 24 hours). adverse indicates promising modality sciatica. should appropriate frequency, well utility second course, diseases colon rectum 11852346 cord injury use oscillating field stimulator safe, reliable, easy. compared outcomes compliant national acute iii plegic patients, results present indicate fda given permission enrollment neurosurgery: 15658119 stroke new methods rehabilitation introduced order reduce disability resulting stroke. twelve months follow-up, effect course patient following ischemic evaluated in-patient (acute subacute period stroke) outpatient (chronic period) basis. beneficial groups przeglad lekarski 17892036 there evidence accelerate healing tissue damage ischemia. undertook investigate injury. attenuated cortical ischemia edema mri anterior coronal level 65% histologic examination, reduced same area 69% 43% striatum. preliminary suggest duration implications bioelectromagnetics 8074737 tinnitus week each noted whether their had completely disappeared, improved, unchanged made worse 45% who completed device, but only 9% placebo). sufferers. otolaryngology allied sciences 8877185 tmj experimental group mouth opening (mean=34.95 41.70 mm, p=0.002), right lateral movement 10.80 left 10.85 0.1) change 39.65 mm), 8.75 mm) 8.80 mm). two follow-up. strongly prfe arthralgia mandibular motion. cranio 14964334 wounds included modalities: standard medication alternating pulsating field. proved highly effective: wound 3-3.5 times faster treatment–2-3 shorter procedure. clinically-verified partial adhesion-related intestinal obstruction procedure 18 children combined lymphosarcoma involving ileum. volpr onkol 11147428 radio adjunct basic care 3 large, long-standing (6 years) stage iv pressure ulcers unresponsive therapy. ulcer healed 4 weeks, heel size 95% 7 months, closure 11 months. conclusion: care, if administered early therapy, might avoid lengthy hospitalizations repeated surgical procedures necessary uncontrolled ulcers, reducing overall cost chronically ill injured plastic reconstructive 19008935
